Evidence-Based Clinical Guidelines for Multidisciplinary Spine Care
Diagnosis and Treatment of Adults with Neoplastic Vertebral Fractures
Recommendations
Cost-Effectiveness
Cost-Effectiveness Question 1: In the treatment of neoplastic vertebral fractures, what is the comparative cost-effectiveness of
(a) Medical and/or radiation therapy alone vs
(b) Vertebral augmentation (with or without radiation therapy) vs
(c) Thermal ablation, radiofrequency ablation or cryoablation with or without augmentation vs
(d) Operative fusion/fixation?
A systematic review of the literature yielded no studies to adequately address this question.
FLASK Future Directions for Research
The work group recommends high-quality studies to better understand cost effectiveness and value propositions from the patient perspective for the treatment of neoplastic vertebral fractures.